| QB | Team | Opponent | |
| 1 | Mason Rudolph | OKL ST | vs Kan |
| 2 | Baker Mayfield | OKL | vs WV |
| 3 | Lamar Jackson | LOU | @ KY |
| 4 | McKenzie Milton | UCF | vs USF |
| 5 | Josh Rosen | UCLA | vs Cal |
| 6 | Khalil Tate | ARIZ | @ AZSt |
| 7 | Eric Dungey | SYR | vs BC |
| 8 | Riley Ferguson | Mem | vs ECU |
| 9 | Justice Hansen | ARK ST | @ ULM |
| 10 | Nick Fitzgerald | MSST | vs Miss |
| 11 | Quinton Flowers | USF | @ UCF |
| 12 | Ben Hicks | SMU | vs Tul |
| 13 | Tyler Rogers | NMST | vs Idaho |
| 14 | Mason Fine | NTEX | @ Rice |
| 15 | Brent Stockstill | MTSU | vs OD |
| 16 | Taylor Lamb | APPST | @ GA St |
| 17 | Trace McSorely | PSU | @ Mary |
| 18 | Josh Jackson | VT | @ UVA |
| 19 | Nathan Rourke | OHIO | @ Buffalo |
| 20 | John Wolford | WF | vs Duke |
| 21 | Drew Lock | MIZ | @ Ark |
| 22 | Mike White | WKU | @ FLInt |
| 23 | Brandon Wimbush | ND | @ Stan |
| 24 | Malik Rosier | MIA | @ Pitt |
| 25 | Kelly Bryant | CLE | @ SCar |
| 26 | Jalen Hurts | BAMA | @ Aub |
| 27 | J.T. Barrett | OSU | @ Mich |
| 28 | Logan Woodside | TOL | vs WMU |
| 29 | Manny Wilkins | AZST | vs Ariz |
| 30 | Nic Shimonek | TT | @ Tex |
| RB | Team | Opponent | |
| 1 | Rashaad Penny | SDST | vs NM |
| 2 | Saquon Barkley | PSU | @ Mary |
| 3 | Devin Singletary | FAU | @ Char |
| 4 | Jonathan Taylor | WIS | @ Minn |
| 5 | Bryce Love | STAN | vs ND |
| 6 | Phillip Lindsay | COL | @ Utah |
| 7 | Derrius Guice | LSU | vs TAMU |
| 8 | Lexington Thomas | UNLV | @ Nev |
| 9 | Justin Jackson | NW | @ Ill |
| 10 | Jarvion Franklin | WMich | @ Tol |
| 11 | Josh Adams | ND | @ Stan |
| 12 | Nick Chubb | UGA | @ GT |
| 13 | Ito Smith | SMiss | @ Mar |
| 14 | Spencer Brown | UAB | vs UTEP |
| 15 | D’Angelo Brewer | Tuls | vs Temp |
| 16 | Justice Hill | OKLST | vs Kan |
| 17 | Royce Freeman | ORE | vs OrST |
| 18 | Patrick Laird | CAL | @ UCLA |
| 19 | Akrum Wadley | IA | @ Neb |
| 20 | Diocemy Saint Juste | HAW | vs BYU |
| 21 | Benny Snell Jr | UK | vs Lou |
| 22 | Myles Gaskin | WAS | vs WAST |
| 23 | Larry Rose III | NMST | vs Idaho |
| 24 | Rodney Anderson | OKL | vs WV |
| 25 | David Montgomery | IAST | @ K St |
| 26 | Ryan Nall | ORST | @ Ore |
| 27 | John Kelly | TENN | vs Vandy |
| 28 | J.K. Dobbins | OSU | @ Mich |
| 29 | Travis Homer | MIA | @ Pitt |
| 30 | Alexander Mattison | BSU | @ Fres |
| 31 | Kerryon Johnson | AUB | vs Bama |
| 32 | Damien Harris | BAMA | @ Aub |
| WR | Team | Opponent | |
| 1 | Anthony Miller | Mem | vs ECU |
| 2 | James Washington | OKL ST | vs Kan |
| 3 | Trey Quinn | SMU | vs Tul |
| 4 | Steve Ishmael | SYR | vs BC |
| 5 | N’Keal Harry | AZST | vs Ariz |
| 6 | Wyatt Demps | NEV | vs UNLV |
| 7 | David Sills | WV | @ Okl |
| 8 | Jordan Lasley | UCLA | vs Cal |
| 9 | Diontae Johnson | TOL | vs WMU |
| 10 | Simmie Cobbs | IND | @ Pur |
| 11 | Cam Phillips | VT | @ UVA |
| 12 | Cedrick Wilson | BSU | @ Fres |
| 13 | Penny Hart | GaST | vs App St |
| 14 | Courtland Sutton | SMU | vs Tul |
| 15 | James Gardner | MiaOH | @ Ball |
| 16 | Ty Lee | MDTN | vs ECU |
| 17 | Korey Robertson | SMiss | @ Mar |
| 18 | Marcell Ateman | OKL ST | vs Kan |
| 19 | AJ Brown | MISS | @ MSST |
| 20 | Ervin Phillips | SYR | vs BC |
| 21 | Tre’Quan Smith | UCF | vs USF |
| 22 | DJ Moore | MD | vs PSU |
| 23 | Gary Jennings | WV | @ Okl |
| 24 | Christian Kirk | TAMU | @ LSU |
| 25 | Keke Coutee | TT | @ Tex |
| 26 | Denzel Mims | BAY | @ TCU |
| 27 | Ka’Raun White | WV | @ Okl |
| 28 | Jon’Vea Johnson | TOL | vs WMU |
| TE | Team | Opponent | |
| 1 | Jaylen Samuels | NCST | vs UNC |
| 2 | Mark Andrews | OKL | vs WV |
| 3 | Jake Roh | BSU | @ Fres |
| 4 | Cam Serigne | WF | vs Duke |
| 5 | Blake Mack | ARK ST | @ ULM |
| 6 | Mike Gesicki | PSU | @ Mary |
| 7 | Matt Bushman | BYU | @ Haw |
| 8 | Christopher Herndon | MIA | @ Pitt |
| 9 | Deon Yelder | WKU | @ FLInt |
| 10 | Ryan Yurachek | MAR | vs SMiss |
| 11 | Harrison Bryant | FAU | @ Char |
| 12 | Ian Thomas | IND | @ Pur |
| 13 | Noah Fant | IA | @ Neb |
| 14 | Troy Fumagalli | WIS | @ Minn |
| 15 | Melvin Vaughn | OD | @ MDTN |
| D/SPT | Opponent | ||
| 1 | Ohio State | @ Mich | |
| 2 | Wisconsin | @ Minn | |
| 3 | Clemson | @ SCar | |
| 4 | Virginia Tech | @ UVA | |
| 5 | Alabama | @ Aub | |
| 6 | Miami | @ Pitt | |
| 7 | Georgia | @ GT | |
| 8 | Texas | vs TT | |
| 9 | Penn State | @ Mary | |
| 10 | TCU | vs Bay | |
| 11 | Wyoming | @ SJST | |
| 12 | Washington | vs WAST | |
| 13 | LSU | vs TAMU | |
| 14 | Auburn | vs Bama | |
| 15 | Michigan | vs Ohio State | |
